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KMID : 0370220170610060286
Yakhak Hoeji
2017 Volume.61 No. 6 p.286 ~ p.291
Studies on Total Synthesis of Giffonins A and D
Jeong Myeong-Gyo

Choi Hyeon-Jin
Kim Seung-Tae
Yun Hwa-Young
Abstract
A synthetic study toward the total synthesis of giffonins A and D, cyclized diarylheptanoids, is described. The key feature of our synthesis involves efficient formation of the advanced precursors, which consist of entire skeleton of the diarylheptanoids, utilizing regioselective formylation and iodination.
KEYWORD
giffonin A, giffonin D, diaryl ether heptanoid, antioxidant, regioselective reaction
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